Mitchell Research Group

Natural Products Inspired Organic Synthesis: An Enduring Platform for Training Next Generation Scientists

Principal Investigator

BIOGRAPHY

Andy Mitchell obtained a B.S. in Chemistry at Grove City College (PA) in 2001.  He joined the research group of Prof. Daniel Romo at Texas A&M University and completed his Ph.D. in 2008.  After two years as a postodoctoral associate with Prof. Jeffrey W. Bode (moved to ETH-LOC in Zurich, Switzerland in 2010) at the University of Pennsylvania, he joined the Department of Chemistry at Illinois State University as an Assistant Professor in 2010.
 
 
 
CONTACT INFORMATION
 
Illinois State University
Department of Chemistry
Campus Box 4160
Normal, IL 61790-4160
 
Office: SLB Room 311
Office Phone: (309) 438–2697
Fax: (309) 438-5538 (dept)
E-mail: mitchell@ilstu.edu
Web: cas.illinoisstate.edu/sites/tmitche
 
APPOINTMENTS & EDUCATION
 
Illinois State University, Normal, IL (2010-present)
Assistant Professor, Department of Chemistry
 
University of Pennsylvania, Philadelphia, PA (2008-2010)
Postdoctoral Advisor: Professor Jeffrey W. Bode
 
Texas A&M University, College Station, TX (Ph.D. Chemistry, 2008)
Doctoral Advisor: Professor Daniel Romo
 
Grove City College, Grove City, PA (B.S. Chemistry, 2001)
Undergraduate Advisor: Professor Harold L. Conder
 
PUBLICATIONS
 
Simanis, J. A.; Zwick, C. R.; Woodall, E. L.; Goodell, J. R.; Mitchell, T. A. “Further Investigation of Pyranone Activation.” Heterocycles 2015, 91, 149-156. Link
 
Simanis, J. A.; Law, C. M.; Woodall, E. L.; Hamaker, C. G.; Goodell, J. R.; Mitchell, T. A. “Investigation of Oxidopyrylium-Alkene [5+2] Cycloaddition Conjugate Addition Cascade (C3) Sequences.” Chem. Commun. 2014, 50, 9130-9133. Link
 
Shaner, C. E.; Ferrence, G. M.; Mitchell, T. A. “Synthetic Efforts toward the Isoindolinone Core of Muironolide A.” Synlett 201324, 1861-1864. Link
 
Woodall, E. L; Simanis, J. A.; Hamaker, C. G.; Goodell, J. R.; Mitchell, T. A. “Unique Reactivity of anti– and syn-Acetoxypyranones en Route to Oxidopyrylium Intermediates Leading to a Cascade Process.” Org. Lett. 2013, 15, 3270-3273. Link
 
Zhao, C.; Mitchell, T. A.; Vallakati, R.; Pérez, L. M.; Romo, D. “Mechanistic Investigations of the ZnCl2-Mediated Tandem Mukaiyama Aldol-Lactonization (TMAL): Evidence for Asynchronous Concerted Transition States and Discovery of 2-Oxopyridyl Ketene Acetal Variants,” J. Am. Chem. Soc. 2012, 134, 3084-3094. Link
 
Vo, C.-V. T.; Mitchell, T. A.; Bode, J. W. Expanded Substrate Scope and Improved Reactivity of Ether-Forming Cross-Coupling Reactions of Organotrifluoroborates and Acetals,” J. Am. Chem. Soc. 2011, 133, 14082-14089. Link
 
Mitchell, T. A.; Bode, J. W. “Synthesis of Dialkyl Ethers from Organotrifluoroborates and Acetals,” J. Am. Chem. Soc. 2009, 131, 18057–18059.  Link     
 
Mitchell, T. A.; Zhao, C.; Romo, D. “Diastereoselective, Three-Component Cascade Synthesis of Tetrahydrofurans and Tetrahydropyrans Employing the Tandem Mukaiyama Aldol-Lactonization Process,” J. Org. Chem. 2008, 73, 9544–9551. Link
 
Mitchell, T.A.; Zhao, C.; Romo, D. “Highly Diastereoselective, Tandem, Three-Component Synthesis of Tetrahydrofurans from Ketoaldehydes via Silylated β-Lactone Intermediates,” Angew. Chem. Int. Ed. 2008, 47, 5026–5029.  Link 
 
Mitchell, T. A.; Romo, D. “Diastereoselective Synthesis of Tetrahydrofurans via Mead Reductive Cyclization of Keto-β-Lactones Derived from the Tandem Mukaiyama Aldol-Lactonization (TMAL) Process,” J. Org. Chem. 2007, 72, 9053–9059.  Link 
 
Mitchell, T. A.; Romo, D. “Radical Reactions and α-Silylations of Optically Active 4-Trichloromethyl-β-Lactone,” Heterocycles, 2005, 66, 627–637.  Link 

Leave a Reply

You must be logged in to post a comment.

  • Recent News

    Congratulations to Marshall Law for successfully defending his thesis! 7-23-15

    Congratulations to Jasmine, Katya, Laina, Camille, Jessica, and Alexandra for graduating from the Illinois Summer Research Academy! 7-18-14

    Congratulations to Christian Zwick who graduated with his B.S. (Chemistry) in May 2015!

    Congratulations to Brendan Thompson who graduated with his B.S. (Chemistry) in May 2015!

    Congratulations to Stacie Cler who graduated with her B.S. (Chemistry) in May 2015!

    Congratulations to Justin, Christian, Marshall, Erica, and John for their recent paper in Heterocycles! 1-15-15

    Congratulations to Chris Olson who graduated with his B.S. (Chemistry) in December 2014!

    Congratulations to Greg, Alexandria, Jason, Robert, and Kevin for graduating from the Illinois Summer Research Academy! 7-18-14

    Congratulations to Justin, Marshall, Erica, and John for their recent paper in ChemComm! 7-3-14

    Congratulations to Justin Simanis for successfully defending his M.S. thesis! 6-16-14

    Congratulations to Marshall Law who graduated with his B.S. (Biochemistry) in December 2013!

    Congratulations to Erica Woodall for successfully defending her M. S. thesis! 10-14-13

    Congratulations to Courtnay for her recent paper in Synlett! 7-10-13

    Congratulations to Erica, Justin, and John for their recent paper in Organic Letters! 6-21-13

    Congratulations to Erin Mortimer who graduated with her B.S. (Biology) in May 2013!

    Congratulations to Sydney Roche who graduated with her B.S. (Biochemistry) in May 2013!

    Congratulations to Patrick Leszczynski who graduated with his B.S. (Chemistry) in December 2012!

    Congratulations to Courtnay Shaner for successfully defending her M.S. thesis! 9-20-12

    The group was recently awarded a Cottrell College Science Award from the Research Corporation for Scientific Advancement! 7-1-12

    The group was recently awarded a Petroleum Research Fund - Undergraduate New Investigator Award from the American Chemical Society! 9-1-12

    Congratulations to Justin Simanis who graduated with his B.S. (Chemistry) in May 2012!

    Congratulations to Dave Ferge who graduated with his B.A. (English) in May 2012!

    Congratulations to Louis Bajek who graduated with his B.S. (Chemistry) in May 2011!

    Congratulations to Matt Beio who graduated with his B.S. (Biochemistry) in May 2011!